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ELK Biotechnology
SKU:ES8011
GPR56 Rabbit Polyclonal Antibody
GPR56 Rabbit Polyclonal Antibody
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$248.00 USD
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GPR56 Rabbit Polyclonal Antibody
Overview
| Product name: | GPR56 rabbit pAb |
| Alternative Names: | GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 78kD |
| GeneID(Human): | 9289 |
| Human Swiss-Prot No: | Q9Y653 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein .; [ADGRG1 N-terminal fragment]: Secreted .; [ADGRG1 C-terminal fragment]: Membrane raft . Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. . |
| Background: | This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of NIH-3T3 cells using GPR56 Polyclonal Antibody diluted at 1:1000 -
Immunofluorescence analysis of MCF7 cells, using GPR56 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 cells, using GPR56 Antibody. The lane on the right is blocked with the synthesized peptide.
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