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ELK Biotechnology

SKU:ES7948

Claudin-10 Rabbit Polyclonal Antibody

Claudin-10 Rabbit Polyclonal Antibody

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Claudin-10 Rabbit Polyclonal Antibody

Overview

Product name: Claudin-10 rabbit pAb
Alternative Names: CLDN10; Claudin-10; OSP-like protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 25kD
GeneID(Human): 9071
Human Swiss-Prot No: P78369
Cellular localization: Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010],
Species Reactivity: Human; Mouse; Rat
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