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ELK Biotechnology

ES7933

Cyclin H (phospho Thr315) Rabbit Polyclonal Antibody

Cyclin H (phospho Thr315) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Cyclin H (phospho Thr315) Rabbit Polyclonal Antibody

Overview

Product name: Cyclin H (phospho Thr315) rabbit pAb
Alternative Names: CCNH; Cyclin-H; MO15-associated protein; p34; p37
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Cyclin H around the phosphorylation site of Thr315. AA range:274-323
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 34 36kD
GeneID（Human）: 902
Human Swiss-Prot No: P51946
Cellular localization: Nucleus.
Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple t
Species Reactivity: Human;Mouse;Rat
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