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ELK Biotechnology

SKU:ES7898

PIXβ Rabbit Polyclonal Antibody

PIXβ Rabbit Polyclonal Antibody

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PIXβ Rabbit Polyclonal Antibody

Overview

Product name: PIXβ rabbit pAb
Alternative Names: ARHGEF7; COOL1; KIAA0142; P85SPR; PAK3BP; PIXB; Nbla10314; Rho guanine nucleotide exchange factor 7; Beta-Pix; COOL-1; PAK-interacting exchange factor beta; p85
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF7. AA range:311-360
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 80kD
GeneID(Human): 8874
Human Swiss-Prot No: Q14155
Cellular localization: Cell junction, focal adhesion . Cell projection, ruffle . Cytoplasm, cell cortex . Cell projection, lamellipodium . Detected at cell adhesions. A small proportion is detected at focal adhesions.
Background: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016],
Species Reactivity: Human;Mouse;Rat
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