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ELK Biotechnology
SKU:ES7894
CCK-AR Rabbit Polyclonal Antibody
CCK-AR Rabbit Polyclonal Antibody
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CCK-AR Rabbit Polyclonal Antibody
Overview
| Product name: | CCK-AR rabbit pAb |
| Alternative Names: | CCKAR; CCKRA; Cholecystokinin receptor type A; CCK-A receptor; CCK-AR; Cholecystokinin-1 receptor; CCK1-R |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CCKAR. AA range:215-264 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 44kD |
| GeneID(Human): | 886 |
| Human Swiss-Prot No: | P32238 |
| Cellular localization: | Cell membrane; Multi-pass membrane protein. |
| Background: | This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i -
Western blot analysis of lysates from HepG2 and Jurkat cells, using CCKAR Antibody. The lane on the right is blocked with the synthesized peptide.
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