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ELK Biotechnology

ES7833

RUNX1 (phospho Ser249) Rabbit Polyclonal Antibody

RUNX1 (phospho Ser249) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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RUNX1 (phospho Ser249) Rabbit Polyclonal Antibody

Overview

Product name: RUNX1 (phospho Ser249) rabbit pAb
Alternative Names: RUNX1; AML1; CBFA2; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AML1 around the phosphorylation site of Ser276. AA range:242-291
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 49kD
GeneID（Human）: 861
Human Swiss-Prot No: Q01196
Cellular localization: Nucleus.
Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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