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ELK Biotechnology

SKU:ES7832

KLF7 Rabbit Polyclonal Antibody

KLF7 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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KLF7 Rabbit Polyclonal Antibody

Overview

Product name: KLF7 rabbit pAb
Alternative Names: KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human KLF7. AA range:171-220
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 41kD
GeneID(Human): 8609
Human Swiss-Prot No: O75840
Cellular localization: Nucleus .
Background: The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
Species Reactivity: Human;Mouse
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