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ELK Biotechnology
SKU:ES7832
KLF7 Rabbit Polyclonal Antibody
KLF7 Rabbit Polyclonal Antibody
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$248.00 USD
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KLF7 Rabbit Polyclonal Antibody
Overview
| Product name: | KLF7 rabbit pAb |
| Alternative Names: | KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human KLF7. AA range:171-220 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 41kD |
| GeneID(Human): | 8609 |
| Human Swiss-Prot No: | O75840 |
| Cellular localization: | Nucleus . |
| Background: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012], |
| Species Reactivity: | Human;Mouse |
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Western blot analysis of KLF7 Antibody. The lane on the right is blocked with the KLF7 peptide. -
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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