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ELK Biotechnology
SKU:ES7823
Mnk1 (phospho Thr385) Rabbit Polyclonal Antibody
Mnk1 (phospho Thr385) Rabbit Polyclonal Antibody
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$248.00 USD
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Mnk1 (phospho Thr385) Rabbit Polyclonal Antibody
Overview
| Product name: | Mnk1 (phospho Thr385) rabbit pAb |
| Alternative Names: | MKNK1; MNK1; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Mnk1 around the phosphorylation site of Thr385. AA range:351-400 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 42kD |
| GeneID(Human): | 8569 |
| Human Swiss-Prot No: | Q9BUB5 |
| Cellular localization: | [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus. |
| Background: | MAP kinase interacting serine/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012], |
| Species Reactivity: | Human;Mouse;Rat |
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Mnk1 (Phospho-Thr385) Antibody -
Immunohistochemistry analysis of paraffin-embedded human brain, using Mnk1 (Phospho-Thr385) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from COLO205 cells treated with PMA 125ng/ml 30', using Mnk1 (Phospho-Thr385) Antibody. The lane on the right is blocked with the phospho peptide.
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