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ELK Biotechnology
SKU:ES7778
GPT2 Rabbit Polyclonal Antibody
GPT2 Rabbit Polyclonal Antibody
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$248.00 USD
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GPT2 Rabbit Polyclonal Antibody
Overview
| Product name: | GPT2 rabbit pAb |
| Alternative Names: | GPT2; AAT2; ALT2; Alanine aminotransferase 2; ALT2; Glutamate pyruvate transaminase 2; GPT 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | Synthesized peptide derived from GPT2 . at AA range: 190-270 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID（Human）: | 84706 |
| Human Swiss-Prot No: | Q8TD30 |
| Cellular localization: | mitochondrion,mitochondrial matrix, |
| Background: | This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015], |
| Species Reactivity: | Human;Rat;Mouse; |
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