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ELK Biotechnology

ES7775

Catalase (phospho Tyr386) Rabbit Polyclonal Antibody

Catalase (phospho Tyr386) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Catalase (phospho Tyr386) Rabbit Polyclonal Antibody

Overview

Product name: Catalase (phospho Tyr386) rabbit pAb
Alternative Names: CAT; Catalase
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Catalase around the phosphorylation site of Tyr385. AA range:361-410
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 59kD
GeneID（Human）: 847
Human Swiss-Prot No: P04040
Cellular localization: Peroxisome.
Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],
Species Reactivity: Human;Mouse;Rat
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