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ELK Biotechnology

ES7764

CaSR Rabbit Polyclonal Antibody

CaSR Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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CaSR Rabbit Polyclonal Antibody

Overview

Product name: CaSR rabbit pAb
Alternative Names: CASR; GPRC2A; PCAR1; Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor; PCaR1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor. AA range:854-903
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 140kD
GeneID（Human）: 846
Human Swiss-Prot No: P41180
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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