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ELK Biotechnology
SKU:ES7733
ATRIP (phospho Ser224) Rabbit Polyclonal Antibody
ATRIP (phospho Ser224) Rabbit Polyclonal Antibody
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ATRIP (phospho Ser224) Rabbit Polyclonal Antibody
Overview
| Product name: | ATRIP (phospho Ser224) rabbit pAb |
| Alternative Names: | ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser224. AA range:190-239 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 86kD |
| GeneID(Human): | 84126 |
| Human Swiss-Prot No: | Q8WXE1 |
| Cellular localization: | Nucleus . Redistributes to discrete nuclear foci upon DNA damage. |
| Background: | This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using ATRIP (Phospho-Ser224) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from 293 cells treated with UV 15', using ATRIP (Phospho-Ser224) Antibody. The lane on the right is blocked with the phospho peptide.
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