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ELK Biotechnology
SKU:ES7732
ATRIP (phospho Ser68) Rabbit Polyclonal Antibody
ATRIP (phospho Ser68) Rabbit Polyclonal Antibody
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ATRIP (phospho Ser68) Rabbit Polyclonal Antibody
Overview
| Product name: | ATRIP (phospho Ser68) rabbit pAb |
| Alternative Names: | ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser68. AA range:34-83 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 80kD |
| GeneID(Human): | 84126 |
| Human Swiss-Prot No: | Q8WXE1 |
| Cellular localization: | Nucleus . Redistributes to discrete nuclear foci upon DNA damage. |
| Background: | This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of NIH-3T3 cells using Phospho-ATRIP (S68) Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using ATRIP (Phospho-Ser68) Antibody -
Western blot analysis of lysates from NIH/3T3 cells, using ATRIP (Phospho-Ser68) Antibody. The lane on the right is blocked with the phospho peptide.
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