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ELK Biotechnology

ES7699

Caspase-3 (phospho Ser150) Rabbit Polyclonal Antibody

Caspase-3 (phospho Ser150) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Caspase-3 (phospho Ser150) Rabbit Polyclonal Antibody

Overview

Product name: Caspase-3 (phospho Ser150) rabbit pAb
Alternative Names: CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 3 around the phosphorylation site of Ser150. AA range:116-165
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 34kD
GeneID（Human）: 836
Human Swiss-Prot No: P42574
Cellular localization: Cytoplasm.
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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