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ELK Biotechnology
SKU:ES7620
FGF-23 Rabbit Polyclonal Antibody
FGF-23 Rabbit Polyclonal Antibody
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FGF-23 Rabbit Polyclonal Antibody
Overview
| Product name: | FGF-23 rabbit pAb |
| Alternative Names: | FGF23; HYPF; Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 27kD |
| GeneID(Human): | 8074 |
| Human Swiss-Prot No: | Q9GZV9 |
| Cellular localization: | Secreted . Secretion is dependent on O-glycosylation. |
| Background: | This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min. -
Immunofluorescence analysis of HUVEC cells, using FGF23 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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