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ELK Biotechnology
SKU:ES7596
SgK269 Rabbit Polyclonal Antibody
SgK269 Rabbit Polyclonal Antibody
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$248.00 USD
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SgK269 Rabbit Polyclonal Antibody
Overview
| Product name: | SgK269 rabbit pAb |
| Alternative Names: | PEAK1; KIAA2002; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269 |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SGK269. AA range:111-160 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 195kD |
| GeneID(Human): | 79834 |
| Human Swiss-Prot No: | Q9H792 |
| Cellular localization: | Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451). . |
| Background: | This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of SGK269 Antibody. The lane on the right is blocked with the SGK269 peptide. -
Western blot analysis of the lysates from 293 cells using SGK269 antibody. -
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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