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ELK Biotechnology
SKU:ES7588
Microcephalin Rabbit Polyclonal Antibody
Microcephalin Rabbit Polyclonal Antibody
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$248.00 USD
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Microcephalin Rabbit Polyclonal Antibody
Overview
| Product name: | Microcephalin rabbit pAb |
| Alternative Names: | MCPH1; Microcephalin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 93kD |
| GeneID(Human): | 79648 |
| Human Swiss-Prot No: | Q8NEM0 |
| Cellular localization: | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . |
| Background: | This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010], |
| Species Reactivity: | Human;Mouse |
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Western blot analysis of the lysates from HT-29 cells using MCPH1 antibody. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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