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ELK Biotechnology

ES7563

CAD (phospho Thr456) Rabbit Polyclonal Antibody

CAD (phospho Thr456) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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CAD (phospho Thr456) Rabbit Polyclonal Antibody

Overview

Product name: CAD (phospho Thr456) rabbit pAb
Alternative Names: CAD; CAD protein
Applications: IHC;IF;ELISA
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 790
Human Swiss-Prot No: P27708
Cellular localization: Cytoplasm . Nucleus . Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.
Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
Species Reactivity: Human;Mouse
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