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ELK Biotechnology
SKU:ES7552
ZnT-4 Rabbit Polyclonal Antibody
ZnT-4 Rabbit Polyclonal Antibody
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ZnT-4 Rabbit Polyclonal Antibody
Overview
| Product name: | ZnT-4 rabbit pAb |
| Alternative Names: | SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SLC30A4. AA range:71-120 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 47kD |
| GeneID(Human): | 7782 |
| Human Swiss-Prot No: | O14863 |
| Cellular localization: | Endosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . |
| Background: | Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using SLC30A4 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from A549 cells, using SLC30A4 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from 293 cells using SLC30A4 antibody.
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