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ELK Biotechnology

ES7548

CA XII Rabbit Polyclonal Antibody

CA XII Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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CA XII Rabbit Polyclonal Antibody

Overview

Product name: CA XII rabbit pAb
Alternative Names: CA12; Carbonic anhydrase 12; Carbonate dehydratase XII; Carbonic anhydrase XII; CA-XII; Tumor antigen HOM-RCC-3.1.3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CA12. AA range:231-280
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID（Human）: 771
Human Swiss-Prot No: O43570
Cellular localization: Membrane; Single-pass type I membrane protein. Cell membrane .
Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014],
Species Reactivity: Human;Mouse;Rat
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