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ELK Biotechnology
SKU:ES7512
Vitronectin Rabbit Polyclonal Antibody
Vitronectin Rabbit Polyclonal Antibody
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Vitronectin Rabbit Polyclonal Antibody
Overview
| Product name: | Vitronectin rabbit pAb |
| Alternative Names: | VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Vitronectin. AA range:209-258 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 7448 |
| Human Swiss-Prot No: | P04004 |
| Cellular localization: | Secreted, extracellular space .; Parasitophorous vacuole . (Microbial infection) In P.falciparum-infected red blood cells, VTN internalization is detected at the early trophozoite stage (PubMed:29567995). Colocalizes with SERA5 at the schizont stage and with SERA5 P47 at the merozoite surface (PubMed:29567995). . |
| Background: | The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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