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ELK Biotechnology
SKU:ES7489
Vav2 (phospho Tyr142) Rabbit Polyclonal Antibody
Vav2 (phospho Tyr142) Rabbit Polyclonal Antibody
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Vav2 (phospho Tyr142) Rabbit Polyclonal Antibody
Overview
| Product name: | Vav2 (phospho Tyr142) rabbit pAb |
| Alternative Names: | VAV2; Guanine nucleotide exchange factor VAV2; VAV-2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human VAV2 around the phosphorylation site of Tyr142. AA range:108-157 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 101kD |
| GeneID(Human): | 7410 |
| Human Swiss-Prot No: | P52735 |
| Cellular localization: | cytosol,plasma membrane, |
| Background: | VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], |
| Species Reactivity: | Human;Mouse |
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Immunofluorescence analysis of NIH/3T3 cells, using VAV2 (Phospho-Tyr142) Antibody. The picture on the right is blocked with the phospho peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain, using VAV2 (Phospho-Tyr142) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from HeLa cells and K562 cells treated with TNF 20ng/ml 30', using VAV2 (Phospho-Tyr142) Antibody. The lane on the right is blocked with the phospho peptide.
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