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ELK Biotechnology

SKU:ES7476

UDP-GlcDH Rabbit Polyclonal Antibody

UDP-GlcDH Rabbit Polyclonal Antibody

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UDP-GlcDH Rabbit Polyclonal Antibody

Overview

Product name: UDP-GlcDH rabbit pAb
Alternative Names: UGDH; UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human UGDH. AA range:391-440
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID(Human): 7358
Human Swiss-Prot No: O60701
Cellular localization: nucleus,nucleoplasm,cytosol,extracellular exosome,
Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Species Reactivity: Human;Mouse;Rat
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