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ELK Biotechnology

ES7449

Tuberin (phospho Thr1462) Rabbit Polyclonal Antibody

Tuberin (phospho Thr1462) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Tuberin (phospho Thr1462) Rabbit Polyclonal Antibody

Overview

Product name: Tuberin (phospho Thr1462) rabbit pAb
Alternative Names: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462. AA range:1428-1477
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID（Human）: 7249
Human Swiss-Prot No: P49815
Cellular localization: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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