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ELK Biotechnology
SKU:ES7448
Tuberin (phospho Ser939) Rabbit Polyclonal Antibody
Tuberin (phospho Ser939) Rabbit Polyclonal Antibody
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Tuberin (phospho Ser939) Rabbit Polyclonal Antibody
Overview
| Product name: | Tuberin (phospho Ser939) rabbit pAb |
| Alternative Names: | TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Ser939. AA range:905-954 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 200kD |
| GeneID(Human): | 7249 |
| Human Swiss-Prot No: | P49815 |
| Cellular localization: | Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes. |
| Background: | Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 293 cells using Phospho-Tuberin (S939) Polyclonal Antibody -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Tuberin/TSC2 (Phospho-Ser939) Antibody -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Tuberin/TSC2 (Phospho-Ser939) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from 293 cells treated with Anisomycin 25ug/ml 30', using Tuberin/TSC2 (Phospho-Ser939) Antibody. The lane on the right is blocked with the phospho peptide.
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