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ELK Biotechnology

ES7443

TPH1 (phospho Ser260) Rabbit Polyclonal Antibody

TPH1 (phospho Ser260) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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TPH1 (phospho Ser260) Rabbit Polyclonal Antibody

Overview

Product name: TPH1 (phospho Ser260) rabbit pAb
Alternative Names: TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser260. AA range:231-280
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID（Human）: 7166
Human Swiss-Prot No: P17752
Cellular localization: cytosol,neuron projection,
Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009],
Species Reactivity: Human;Mouse;Rat
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