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ELK Biotechnology

ES7399

TLE2 Rabbit Polyclonal Antibody

TLE2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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TLE2 Rabbit Polyclonal Antibody

Overview

Product name: TLE2 rabbit pAb
Alternative Names: TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 110kD
GeneID（Human）: 7089
Human Swiss-Prot No: Q04725
Cellular localization: Nucleus.
Background: function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 6 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5.,tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.,
Species Reactivity: Human;Rat;Mouse;
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