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ELK Biotechnology
SKU:ES7387
PBR Rabbit Polyclonal Antibody
PBR Rabbit Polyclonal Antibody
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$248.00 USD
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PBR Rabbit Polyclonal Antibody
Overview
| Product name: | PBR rabbit pAb |
| Alternative Names: | TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | Synthesized peptide derived from PBR . at AA range: 90-170 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 20kD |
| GeneID(Human): | 706 |
| Human Swiss-Prot No: | P30536 |
| Cellular localization: | Mitochondrion membrane ; Multi-pass membrane protein . |
| Background: | Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night -
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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