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ELK Biotechnology

SKU:ES7354

Treacle Rabbit Polyclonal Antibody

Treacle Rabbit Polyclonal Antibody

Regular price $248.00 USD
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Treacle Rabbit Polyclonal Antibody

Overview

Product name: Treacle rabbit pAb
Alternative Names: TCOF1; Treacle protein; Treacher Collins syndrome protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TCOF1. AA range:41-90
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 152kD
GeneID(Human): 6949
Human Swiss-Prot No: Q13428
Cellular localization: Nucleus, nucleolus .
Background: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
Species Reactivity: Human;Mouse
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