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ELK Biotechnology
SKU:ES7354
Treacle Rabbit Polyclonal Antibody
Treacle Rabbit Polyclonal Antibody
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$248.00 USD
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Treacle Rabbit Polyclonal Antibody
Overview
| Product name: | Treacle rabbit pAb |
| Alternative Names: | TCOF1; Treacle protein; Treacher Collins syndrome protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TCOF1. AA range:41-90 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 152kD |
| GeneID(Human): | 6949 |
| Human Swiss-Prot No: | Q13428 |
| Cellular localization: | Nucleus, nucleolus . |
| Background: | This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008], |
| Species Reactivity: | Human;Mouse |
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TCOF1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from Jurkat, 293, HeLa cells, using TCOF1 Antibody. The lane on the right is blocked with the synthesized peptide.
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