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ELK Biotechnology
SKU:ES7347
TXA synthase Rabbit Polyclonal Antibody
TXA synthase Rabbit Polyclonal Antibody
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$248.00 USD
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TXA synthase Rabbit Polyclonal Antibody
Overview
| Product name: | TXA synthase rabbit pAb |
| Alternative Names: | TBXAS1; CYP5; CYP5A1; Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human TXA synthase. |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 60kD |
| GeneID(Human): | 6916 |
| Human Swiss-Prot No: | P24557 |
| Cellular localization: | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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