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ELK Biotechnology
SKU:ES7327
Synapsin I Rabbit Polyclonal Antibody
Synapsin I Rabbit Polyclonal Antibody
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$248.00 USD
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Synapsin I Rabbit Polyclonal Antibody
Overview
| Product name: | Synapsin I rabbit pAb |
| Alternative Names: | SYN1; Synapsin-1; Brain protein 4.1; Synapsin I |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Synapsin1. AA range:26-75 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 80kD |
| GeneID(Human): | 6853 |
| Human Swiss-Prot No: | P17600 |
| Cellular localization: | Cell junction, synapse. Golgi apparatus . |
| Background: | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of NIH-3T3 cells using Synapsin I Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synapsin1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from NIH/3T3 cells, treated with Nocodazole 1ug/ml 16h, using Synapsin1 Antibody. The lane on the right is blocked with the synthesized peptide.
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