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ELK Biotechnology
SKU:ES7318
VAMP-1/2/3 Rabbit Polyclonal Antibody
VAMP-1/2/3 Rabbit Polyclonal Antibody
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VAMP-1/2/3 Rabbit Polyclonal Antibody
Overview
| Product name: | VAMP-1/2/3 rabbit pAb |
| Alternative Names: | VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human VAMP-1/2/3. AA range:21-70 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 13kD |
| GeneID(Human): | 6843/6844/9341 |
| Human Swiss-Prot No: | P23763/P63027/Q15836 |
| Cellular localization: | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 2]: Cytoplasmic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein . |
| Background: | Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of mouse-brain cells using VAMP-1/2/3 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe -
Immunohistochemistry analysis of VAMP-1/2/3 antibody in paraffin-embedded human lung carcinoma tissue.
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