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ELK Biotechnology
SKU:ES7297
Stat4 (phospho Tyr693) Rabbit Polyclonal Antibody
Stat4 (phospho Tyr693) Rabbit Polyclonal Antibody
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Stat4 (phospho Tyr693) Rabbit Polyclonal Antibody
Overview
| Product name: | Stat4 (phospho Tyr693) rabbit pAb |
| Alternative Names: | STAT4; Signal transducer and activator of transcription 4 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human Stat4 (phospho Tyr693) |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 85kD |
| GeneID(Human): | 6775 |
| Human Swiss-Prot No: | Q14765 |
| Cellular localization: | Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation. |
| Background: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absor -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using STAT4 (Phospho-Tyr693) Antibody -
Immunohistochemistry analysis of paraffin-embedded human breast cancer, using STAT4 (Phospho-Tyr693) Antibody. The picture on the right is blocked with the STAT4 (Phospho-Tyr693) peptide.
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