1 1

ELK Biotechnology

ES7295

Stat2 (phospho Tyr631) Rabbit Polyclonal Antibody

Stat2 (phospho Tyr631) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

Stat2 (phospho Tyr631) Rabbit Polyclonal Antibody

Overview

Product name: Stat2 (phospho Tyr631) rabbit pAb
Alternative Names: STAT2; Signal transducer and activator of transcription 2; p113
Applications: IHC;IF;ELISA
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr631. AA range:597-646
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 6773
Human Swiss-Prot No: P52630
Cellular localization: Cytoplasm . Nucleus . Translocated into the nucleus upon activation by IFN-alpha/beta. .
Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Species Reactivity: Human;Mouse;Rat
View full details