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ELK Biotechnology

ES7287

RO60 Rabbit Polyclonal Antibody

RO60 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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RO60 Rabbit Polyclonal Antibody

Overview

Product name: RO60 rabbit pAb
Alternative Names: TROVE2; RO60; SSA2; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID（Human）: 6738
Human Swiss-Prot No: P10155
Cellular localization: Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
Background: disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,
Species Reactivity: Human;Rat;Mouse;
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