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ELK Biotechnology

SKU:ES7273

SRF (phospho Ser103) Rabbit Polyclonal Antibody

SRF (phospho Ser103) Rabbit Polyclonal Antibody

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SRF (phospho Ser103) Rabbit Polyclonal Antibody

Overview

Product name: SRF (phospho Ser103) rabbit pAb
Alternative Names: SRF; Serum response factor; SRF
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Ser99. AA range:71-120
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID(Human): 6722
Human Swiss-Prot No: P11831
Cellular localization: Nucleus .
Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],
Species Reactivity: Human;Mouse;Rat
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