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ELK Biotechnology

ES7245

SNAI 1 (phospho Ser246) Rabbit Polyclonal Antibody

SNAI 1 (phospho Ser246) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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SNAI 1 (phospho Ser246) Rabbit Polyclonal Antibody

Overview

Product name: SNAI 1 (phospho Ser246) rabbit pAb
Alternative Names: SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SNAI1 around the phosphorylation site of Ser246. AA range:215-264
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 29kD
GeneID（Human）: 6615
Human Swiss-Prot No: O95863
Cellular localization: Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
Background: snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Monkey
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