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ELK Biotechnology
SKU:ES7200
CYP3A43 Rabbit Polyclonal Antibody
CYP3A43 Rabbit Polyclonal Antibody
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$248.00 USD
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CYP3A43 Rabbit Polyclonal Antibody
Overview
| Product name: | CYP3A43 rabbit pAb |
| Alternative Names: | CYP3A43; Cytochrome P450 3A43 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A43. AA range:231-280 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 57kD |
| GeneID(Human): | 64816 |
| Human Swiss-Prot No: | Q9HB55 |
| Cellular localization: | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Background: | cytochrome P450 family 3 subfamily A member 43(CYP3A43) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of lysates from Jurkat cells, using Cytochrome P450 3A43 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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