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ELK Biotechnology
SKU:ES7173
Artemis Rabbit Polyclonal Antibody
Artemis Rabbit Polyclonal Antibody
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$248.00 USD
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Artemis Rabbit Polyclonal Antibody
Overview
| Product name: | Artemis rabbit pAb |
| Alternative Names: | DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein |
| Applications: | IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Artemis. AA range:482-531 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 64421 |
| Human Swiss-Prot No: | Q96SD1 |
| Cellular localization: | Nucleus . |
| Background: | This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunofluorescence analysis of NIH/3T3 cells, using Artemis Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Artemis Antibody. The picture on the right is blocked with the synthesized peptide.
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