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ELK Biotechnology

ES7172

Artemis (phospho Ser516) Rabbit Polyclonal Antibody

Artemis (phospho Ser516) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Artemis (phospho Ser516) Rabbit Polyclonal Antibody

Overview

Product name: Artemis (phospho Ser516) rabbit pAb
Alternative Names: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Artemis around the phosphorylation site of Ser516. AA range:482-531
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 78kD
GeneID（Human）: 64421
Human Swiss-Prot No: Q96SD1
Cellular localization: Nucleus .
Background: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Species Reactivity: Human;Mouse
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