1 1

ELK Biotechnology

ES7123

Na+ CP type VIIα Rabbit Polyclonal Antibody

Na+ CP type VIIα Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

Na+ CP type VIIα Rabbit Polyclonal Antibody

Overview

Product name: Na+ CP type VIIα rabbit pAb
Alternative Names: SCN7A; SCN6A; Sodium channel protein type 7 subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type VII subunit alpha
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human SCN7A. AA range:771-820
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID（Human）: 6332
Human Swiss-Prot No: Q01118
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],
Species Reactivity: Human;Monkey
View full details