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ELK Biotechnology
SKU:ES7122
Na+ CP type IVα Rabbit Polyclonal Antibody
Na+ CP type IVα Rabbit Polyclonal Antibody
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Na+ CP type IVα Rabbit Polyclonal Antibody
Overview
| Product name: | Na+ CP type IVα rabbit pAb |
| Alternative Names: | SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4 |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SCN4A. AA range:431-480 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 200kD |
| GeneID(Human): | 6329 |
| Human Swiss-Prot No: | P35499 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . |
| Background: | Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western blot analysis of SCN4A Antibody. The lane on the right is blocked with the SCN4A peptide. -
Western blot analysis of the lysates from COLO205 cells using SCN4A antibody. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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