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ELK Biotechnology

SKU:ES7122

Na+ CP type IVα Rabbit Polyclonal Antibody

Na+ CP type IVα Rabbit Polyclonal Antibody

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Na+ CP type IVα Rabbit Polyclonal Antibody

Overview

Product name: Na+ CP type IVα rabbit pAb
Alternative Names: SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human SCN4A. AA range:431-480
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID(Human): 6329
Human Swiss-Prot No: P35499
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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