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ELK Biotechnology
SKU:ES7083
Rsk-1 Rabbit Polyclonal Antibody
Rsk-1 Rabbit Polyclonal Antibody
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$248.00 USD
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Rsk-1 Rabbit Polyclonal Antibody
Overview
| Product name: | Rsk-1 rabbit pAb |
| Alternative Names: | RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human p90 RSK. AA range:539-588 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 80kD |
| GeneID(Human): | 6195 |
| Human Swiss-Prot No: | Q15418 |
| Cellular localization: | Nucleus. Cytoplasm. |
| Background: | ribosomal protein S6 kinase A1(RPS6KA1) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemical analysis of paraffin-embedded Human colon cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorb -
Immunofluorescence analysis of COS7 cells, using p90 RSK Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using p90 RSK Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from NIH/3T3 cells, treated with PMA 125ng/ml 30', using p90 RSK Antibody. The lane on the right is blocked with the synthesized peptide.
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