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ELK Biotechnology

ES6976

Rad52 (phospho Tyr104) Rabbit Polyclonal Antibody

Rad52 (phospho Tyr104) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Rad52 (phospho Tyr104) Rabbit Polyclonal Antibody

Overview

Product name: Rad52 (phospho Tyr104) rabbit pAb
Alternative Names: RAD52; DNA repair protein RAD52 homolog
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RAD52 around the phosphorylation site of Tyr104. AA range:70-119
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 46kD
GeneID（Human）: 5893
Human Swiss-Prot No: P43351
Cellular localization: Nucleus .
Background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014],
Species Reactivity: Human;Mouse;Monkey
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