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ELK Biotechnology

ES6862

Nicalin Rabbit Polyclonal Antibody

Nicalin Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Nicalin Rabbit Polyclonal Antibody

Overview

Product name: Nicalin rabbit pAb
Alternative Names: NCLN; Nicalin; Nicastrin-like protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 63kD
GeneID（Human）: 56926
Human Swiss-Prot No: Q969V3
Cellular localization: Endoplasmic reticulum membrane ; Single-pass membrane protein .
Background: function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,
Species Reactivity: Human;Mouse;Rat
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