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ELK Biotechnology

ES6819

NXF3 Rabbit Polyclonal Antibody

NXF3 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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NXF3 Rabbit Polyclonal Antibody

Overview

Product name: NXF3 rabbit pAb
Alternative Names: NXF3; TAPL3; Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NXF3. AA range:72-121
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID（Human）: 56000
Human Swiss-Prot No: Q9H4D5
Cellular localization: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.
Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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