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ELK Biotechnology
SKU:ES6816
ERK 3 (phospho Ser189) Rabbit Polyclonal Antibody
ERK 3 (phospho Ser189) Rabbit Polyclonal Antibody
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ERK 3 (phospho Ser189) Rabbit Polyclonal Antibody
Overview
| Product name: | ERK 3 (phospho Ser189) rabbit pAb |
| Alternative Names: | MAPK6; ERK3; PRKM6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ERK3 around the phosphorylation site of Ser189. AA range:155-204 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 90kD |
| GeneID(Human): | 5597 |
| Human Swiss-Prot No: | Q16659 |
| Cellular localization: | Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. . |
| Background: | The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using ERK3 (Phospho-Ser189) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from mouse brain, using ERK3 (Phospho-Ser189) Antibody. The lane on the right is blocked with the phospho peptide.
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