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ELK Biotechnology

ES6770

Axl (phospho Tyr691) Rabbit Polyclonal Antibody

Axl (phospho Tyr691) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Axl (phospho Tyr691) Rabbit Polyclonal Antibody

Overview

Product name: Axl (phospho Tyr691) rabbit pAb
Alternative Names: AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AXL around the phosphorylation site of Tyr691. AA range:657-706
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID（Human）: 558
Human Swiss-Prot No: P30530
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Species Reactivity: Human;Mouse;Rat
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