1 1

ELK Biotechnology

ES6767

PKC β (phospho Ser661) Rabbit Polyclonal Antibody

PKC β (phospho Ser661) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

PKC β (phospho Ser661) Rabbit Polyclonal Antibody

Overview

Product name: PKC β (phospho Ser661) rabbit pAb
Alternative Names: PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PKCB around the phosphorylation site of Ser661. AA range:622-671
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 77kD
GeneID（Human）: 5579
Human Swiss-Prot No: P05771
Cellular localization: Cytoplasm . Nucleus . Membrane ; Peripheral membrane protein .
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stres
Species Reactivity: Human;Mouse;Rat
View full details