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ELK Biotechnology

ES6733

AMPKα1 (phospho Ser496) Rabbit Polyclonal Antibody

AMPKα1 (phospho Ser496) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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AMPKα1 (phospho Ser496) Rabbit Polyclonal Antibody

Overview

Product name: AMPKα1 (phospho Ser496) rabbit pAb
Alternative Names: PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK1 around the phosphorylation site of Ser496. AA range:451-500
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 62kD
GeneID（Human）: 5562
Human Swiss-Prot No: Q13131
Cellular localization: Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .
Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat;Canine

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